Tricarboxylic acids and derivatives
TARGETMOL CHEMICALS INC Zoledronic acid monohydrate
Also available in 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity. Purity ≥95%
Medchemexpress LLC Pacritinib (citrate) | 1228923-42-9 | 99.7% | 664.70 | 1 ML
Pacritinib (SB1518) citrate is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). It also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). This compound can be used for the research of acute myeloid leukemia (AML) and myelofibrosis (MF).
- Potent inhibitor of wild-type JAK2 (IC50=23 nM)
- Potent inhibitor of JAK2V617F mutant (IC50=19 nM)
- Inhibits FLT3 (IC50=22 nM)
- Inhibits FLT3D835Y mutant (IC50=6 nM)
- Used for research in acute myeloid leukemia (AML) and myelofibrosis (MF)
Teknova 20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
Sigma Aldrich Fine Chemicals Biosciences Sodium citrate tribasic dihydrate for molecular biology, >=99% | 6132-04-3 | MFCD00150031 | 10KG
Sodium citrate tribasic dihydrate for molecular biology, >=99% | Purity: >=99% | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 10KG
Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 219.23
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
- Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
eMolecules 23142-01-0 | Pentoxyverine citrate | MFCD00055697 | 1g
Ambeed | rel-(3R4S5S6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2345-tetraol | 1g | 649269182 | A1497324 | 54-17-1 | MFCD00063684 | 180.156 | C6H12O6
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Medchemexpress LLC Azido-PEG6-CH2COOH | 880129-82-8 | ≥98.0% | 365.38 | 1 G
Azido-PEG6-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is a click chemistry reagent, featuring an azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It also facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Integral to PROTACs that selectively degrade target proteins