Tricarboxylic acids and derivatives
eMolecules 59085-15-3 | 4-(2-Carboxyethyl)-4-nitro heptanedioic acid | MFCD00077684 | 25g
Combi-Blocks | 4-(2-Carboxyethyl)-4-nitro heptanedioic acid | 25g | 495744957 | QK-4724 | 95.000 | 59085-15-3 | MFCD00077684 | 277.229 | C10H15NO8
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Research Products International Corp Sod Citrate Tris Salt Di 10 KG
CAS Number: 6132-04-3
Molecular Formula: C6H5Na3O7 • 2H2O
Molecular Weight: 294.1
![eMolecules 2902-68-3 | IODOSODILACTONE | AstaTech | MFCD24386358 | 290.012 | C8H3IO4 | 98.000 | O=C1O[I]2OC(=O)c3cccc1c23 | 0.25g | 448281327](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455953.PNG-250.jpg)
eMolecules 2902-68-3 | IODOSODILACTONE | AstaTech | MFCD24386358 | 290.012 | C8H3IO4 | 98.000 | O=C1O[I]2OC(=O)c3cccc1c23 | 0.25g | 448281327
IODOSODILACTONE | AstaTech | 2902-68-3 | MFCD24386358 | 290.012 | C8H3IO4 | 98.000 | O=C1O[I]2OC(=O)c3cccc1c23 | 0.25g | 448281327
Medchemexpress LLC 5,8,11-Trioxa-2-azatridecanedioic acid, 1-(1,1-dimethylethyl) ester | 462100-06-7 | ≥97.0% | 307.34 | 250 MG
Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTAC. PROTACs (Proteolysis Targeting Chimeras) consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Suitable for PROTAC synthesis
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Sigma Aldrich Fine Chemicals Biosciences Triethyl citrate >=99%, FCC, FG | 77-93-0 | MFCD00009201 |
Triethyl citrate >=99%, FCC, FG | Purity: >=99% | Mol Wt: 276.28 | 77-93-0 | MFCD00009201 |
Medchemexpress LLC (Z)-aconitic acid | 585-84-2 | MFCD00063184 | 99.3% | 174.11 g/mol | C6H6O6 | 5 MG
(Z)-aconitic acid is a small-molecule endogenous metabolite (cis-aconitic acid) reported to act as a glutamate decarboxylase inhibitor with activity that includes reduction of IκB-α phosphorylation and inhibition of inflammatory responses; supplied as a solid for research use.
- Molecular formula C6H6O6 and molecular weight 174.11 g/mol.
- High reported purity (99.28%).
- Reported activity as a glutamate decarboxylase inhibitor and modulator of IκB-α phosphorylation.
- Applicable to research on inflammatory and metabolic pathways.
- Powder stability: -20°C for long-term storage; defined solvent storage conditions available.
Medchemexpress LLC Sodium citrate monobasic | 18996-35-5 | 98.0% | 214.11 | 500 G
Sodium citrate monobasic is a natural preservative and food tartness enhancer. It induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. It can cause oxidative damage of the liver by decreasing antioxidative enzyme activities. It is also an acidulant, emulsifier, sequestrant, and buffering agent used across many industries.
- Solid appearance
- White to off-white color
- Store at room temperature, keep dry and cool
- In solvent, store at -80°C for 1 year or -20°C for 6 months
Medchemexpress LLC Dicresulene diammoni 50mg | 50MG
Dicresulene diammonium is an impurity of Policresulen an organic acid with hemostatic antimicrobial and antiviral activities[1 [2
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.2% | 10 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound also functions as a PEG-based PROTAC linker for the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Used in the synthesis of antibody-drug conjugates
- Used in the synthesis of PROTACs
- Molecular formula: C29H39NO10
- Molecular weight: 561.62
- Soluble in DMSO at 100 mg/mL (178.06 mM); requires ultrasonic
Medchemexpress LLC ζ-Stat trisodium | 31894-34-5 | 97.0% | 450.31 g/mol | C10H5Na3O10S3 | 5MG
ζ-Stat trisodium (trisodium;8-hydroxynaphthalene-1,3,6-trisulfonate) is the trisodium salt of NSC37044 and a selective inhibitor of atypical protein kinase C zeta (PKC-ζ). It is provided as a light yellow to light brown solid for biochemical and cellular research and has been reported to reduce melanoma cell proliferation and induce apoptosis in vitro.
Medchemexpress LLC Sparfosic acid trisodium | 70962-66-2 | 98.0% | 321.06 | 100 MG
Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase, an enzyme that catalyzes the second step of de novo pyrimidine biosynthesis. It synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines. This product is for research use only and not intended for sale to patients.
- Potent inhibitor of aspartate transcarbamoyl transferase.
- Synergistically enhances cytotoxicity of 5-FU and IFN against human colon cancer cell lines.
- Causes apoptosis in resistant Br1 cells.
- Leads to progressive accumulation of cells in S phase and activation of an apoptotic pathway.
- Increases lifespan and is curative in mice models of B16 melanoma and Lewis lung carcinoma.
Medchemexpress LLC PEG3-O-CH2COOH (PROTAC Linker 8) | 51951-05-4 | ≥95.0% | 100 MG
PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker designed for use in the synthesis of SNIPERs. These SNIPERs recruit inhibitor of apoptosis protein (IAP) ubiquitin ligases to specifically degrade targeted proteins, offering a valuable tool for research applications.
- PEG-based PROTAC linker
- Used in the synthesis of SNIPERs
- Recruits inhibitor of apoptosis protein (IAP) ubiquitin ligases
- Designed to specifically degrade targeted proteins
- For research use only
Selleck Chemical LLC Sodium citrate dihydrate
Sodium citrate dehydrate (Trisodium citrate dihydrate Citric acid trisodium salt dihydrate) is the preferred anticoagulant
![Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 500 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660392.jpg-250.jpg)
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 500 G
Sodium Citrate, Trisodium Salt, Dihydrate, laboratory grade, is provided in a convenient 500g package for smaller-scale laboratory applications. Sodium citrate is an essential reagent for maintaining a stable pH in various laboratory protocols, particularly in the preparation of buffers for biochemical assays, protein purification, and molecular biology applications. The trisodium salt form of sodium citrate ensures high buffering capacity and stability across a range of pH values. This reagent is commonly used in the preparation of anticoagulant solutions, as well as in enzymatic reactions where precise pH control is required. Ideal for research and educational labs requiring moderate quantities of buffer preparation reagents.
Medchemexpress LLC Pacritinib citrate | 1228923-42-9 | 99.7% | 664.70 | 5 MG
Pacritinib citrate is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). It also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). Pacritinib citrate can be used for the research of acute myeloid leukemia (AML) and myelofibrosis (MF).
- Potent inhibitor of wild-type JAK2 (IC50=23 nM)
- Potent inhibitor of JAK2V617F mutant (IC50=19 nM)
- Inhibits FLT3 (IC50=22 nM)
- Inhibits FLT3D835Y mutant (IC50=6 nM)
- Can be used for the research of acute myeloid leukemia (AML)
- Can be used for the research of myelofibrosis (MF)